Some people are replacing their seats with a Corbin leather seat, which costs the best part of $300, takes a month or so to ship, then can take a thousand miles or so to break in. Myself... I would not bother........
Corbin Motorcycle Seats & Accessories | Kawasaki Z1000 | 800-538-7035
(the link says Kawazaki Z1000 for some reason, but it takes you to their Honda CBR250R page).
I reckon sheepskin is a better, and simpler solution.
For less than $60 you can get a sheepskin Butt Pad from Alaska Leather, shipped within a few days, and is instantly comfortable.
http://www.alaskaleatheronline.com/servlet/StoreFront
In the early 1990's I picked up an off-cut of sheepskin for less than $10 from a sheepskin rug shop. On the seat of my CB250RS when touring Europe, it was like riding a magic carpet.
I have used sheepskin for long hauls ever since.
My only other suggestion is to travel light; just take the essentials. Don't carry a whole lot of stuff you might need..... you will probably use little, if any of the extra stuff.
Don't get too specialised in your riding gear; wear comfortable gear that can double as casual wear when you are off your bike.
Take a camera, take plenty of photos......... and post them for the rest of us to see.
My only regret is not having more photos of my journeys in days gone by, most of whch were in the days before digital cameras. Film was a hassle when my home was half way around the world, so I took very few photos. I have not been touring recently, but hope to get on the road again in future..... with a camera.